Welcome to Single Molecule Biophysics Lab

​Our group investigates the structural dynamics, molecular recognition, and functional behavior of DNA and DNA-based nanostructures. We combine single-molecule and fluorescence-based biophysical approaches with molecular modelling and simulation to understand how DNA conformational heterogeneity governs interactions and biological function. Our research focuses on non-canonical DNA structures, including G-quadruplexes, i-motifs, and Holliday junctions, as well as programmable DNA nanostructures and their interactions with proteins. By connecting molecular structure, dynamics, and function across different length and time scales, we aim to uncover fundamental principles of DNA recognition and organization and develop new approaches for understanding genome maintenance and designing functional biomolecular systems

Sneak Peek

                    And more to come...........

We are actively looking for PhD students to work on these and other interesting projects in the lab​
Join us!!